Most Challenging US Infectious Disease Outbreaks

Among the most challenging infectious disease outbreaks in US history are the 1918 H1N1 influenza pandemic, the ongoing HIV/AIDS epidemic since the 1980s, and the recent COVID-19 pandemic (2020-2023).

Sources

• The Worst Outbreaks in U.S. History - Healthline
• Major Pandemics of the Modern Era | Council on Foreign Relations
• List of disease outbreaks in the United States - Wikipedia

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